Lead Poisoning Due to Adulterated Marijuana in Leipzig Indication for chelator therapy should be defined critically: Indication for Chelator Therapy Should Be Defined Critically

Colistin: how should it be dosed for the critically ill?

Colistin, an "old" polymyxin antibiotic, is increasingly being used as last-line treatment against infections caused by multidrug-resistant gram-negative bacteria. It is administered in patients, parenterally or by inhalation, as its inactive prodrug colistin methanesulfonate (CMS). Scientifically based recommendations on how to optimally dose colistin in critically ill patients have become ava...

Should chelation therapy be abandoned ?

I-14: Assisted Reproduction and Religion What Consideration Should Be and Should Not Be Relevant,

Several important issues are pertinent to an ethical discussion of the new technology today grouped under the name Assisted Reproduction Technology (ART). This is a moral imperative because each of us must decide what is to be considered ethically acceptable in assisted reproduction. Reflecting on the ethical dimension of ‘creating’ a new human life can play a major role in ensuring that in eac...

Debate: Albumin administration should be avoided in the critically ill

The benefit of albumin administration in the critically ill patient is unproven. Epidemiological evidence suggests that there is an increase in death among patients with burns, hypoalbuminaemia, and hypotension treated with human albumin solution (HAS). In critical illness, hypoalbuminaemia is a result of transcapillary leak, decreased synthesis, large volume body fluid losses, and dilution cau...

Should selective digestive decontamination be used in critically ill patients?

Healthcare associated infection represents a major burden for critically ill patients; a recent point prevalence survey by the Health Protection Agency observed that 23.4% of patients in intensive care units had evidence of a healthcare associated infection.Ventilator associated pneumonia remains the leading cause of nosocomial infection in this population, and, although recent estimates of att...